HLA-A29 negative Birdshot-like chorioretinopathy associated with common variable immunodeficiency

Common variable immunodeficiency associated with birdshot-like chorioretinopathy.

Common variable immunodeficiency (CVID) is a primary hypogammaglobulinemia. It is associatedwith autoimmunephenomena, such as cytopenia, Sjögren syndrome, inflammatory bowel disease, and arthritis. There have been a number of reported cases of autoimmune disorders that involve the retina in association with CVID. Birdshot retinochoroidopathy is a rare, chronic disorder that typically occurs in ...

HLA-A29-Positive Uveitis: Birdshot Chorioretinopathy, What Else?

Birdshot chorioretinopathy (BSCR) is a relatively rare form of uveitis, which is strongly correlated with the histocompatibility leukocyte antigen (HLA)-A29 class I type. Nevertheless, HLA typing is not diagnostic. The purpose of the present study was to retrospectively evaluate the ocular manifestations associated with the presence of HLA-A29 other than typical BSCR. Charts of consecutive pati...

Why birdshot retinochoroiditis should rather be called ‘HLA-A29 uveitis’?

BIRDSHOT RETINOCHOROIDITIS: THE ORIGINS OF THE DISEASE NAME Birdshot retinochoroiditis (BRC) is a uveitis predominantly affecting the posterior segment of the eye with dual, independent retinal and choroidal inflammation and almost only seen in Caucasians. 2 Ryan and Maumenee first described the bilateral retinochoroidal inflammatory disease in early 1980, reporting on 13 patients. These author...

Double trouble: a patient with both HLA-B27 anterior uveitis and HLA-A29 birdshot chorioretinitis

BACKGROUND Birdshot chorioretinitis (BSCR) is a rare ocular inflammatory disorder associated with HLA-A29 and characterized by bilateral choroidal lesions, vitritis, macular edema, and retinal vasculitis. Ocular inflammation associated with HLA-B27 is typically a recurrent, unilateral, acute anterior uveitis (AAU) that is frequently associated with ankylosing spondylitis (AS). To date, there ar...

Birdshot chorioretinopathy